I have only been using C E Peptides for a couple of weeks, but I like it so far. It's a bit early to tell if I will see a noticeable difference in my skin as I have been using serums for the last couple of years. The one thing I will say about it is that the recommended amount of 2-3 drops is really not enough to be able to spread it on my face and neck. I find I have to use 6 drops to ensure I have enough. So I am worried that the bottle of serum is not going to last very long.